The bioavailability of the drug is 90 percent. Lorazepam is rapidly absorbed when given orally. This binding results in an increase in the GABA inhibitory effects, which translates as an increase in the flow of chloride ions into the cells, causing hyperpolarization and stabilization of the cellular plasma membrane. Lorazepam binds to the benzodiazepine receptors in the postsynaptic GABA (gamma-aminobutyric acid)-A ligand-gated chloride channel neuron at different sites of the central nervous system.

These drugs work by relaxing the activities in the brain and the nerves.

Lorazepam is a short-acting benzodiazepine, often referred to as a sedative or tranquilizer. Lorazepam is a Schedule IV controlled substance which means the drug has the potential for misuse and dependence.

Benzodiazepines are available only on doctors prescriptions and can be taken by adults and children aged 13 and above. Benzodiazepines are central nervous system depressants that slow down the activities in the nervous system. Lorazepam is a benzodiazepine medication used as a sedative and treats anxiety disorder.

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